NIH: Youth With HIV May Lack Immunity To Measles, Mumps, Rubella

nih-logo-blueUp to one-half of youth infected with HIV around the time of birth may not have sufficient immunity to ward off measles, mumps, and rubella—even though they may have been vaccinated against these diseases, according to a new estimate from the National Institutes of Health.

It is based on a study of more than 600 children and youth exposed to HIV in the womb, said George Siberry, medical officer in the Maternal and Pediatric Infectious Disease Branch of NIH’s Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

“Having a high level of immunity to measles, mumps, and rubella is important not only for an individual’s health, but also for preventing disease outbreaks in the larger community,” Siberry said. “Individuals infected with HIV at birth who did not have the benefit of combined antiretroviral therapy before they were vaccinated should speak with their physician about whether they need a repeated course of the vaccine.”

From 2007-2009, the researchers enrolled children ages 7 to 15 from 15 sites across the United States and Puerto Rico. Participants were part of the Pediatric HIV/AIDS Cohort Study (PHACS), an NIH-funded follow-up study of individuals exposed to HIV in the womb.  

On average, the HIV-exposed children were much less likely to have protective levels of antibodies against measles, mumps, and rubella than did the control group. HIV-exposed children who started combined antiretroviral therapy before receiving their MMR vaccine doses were more likely to have protective levels of antibodies against all three diseases.


About Frank Klimko

Frank Klimko is a nationally known journalist, grants expert and speech writer/speaker. He has years of experience helping nonprofits devise lists of the right funding opportunities and secure funding from these foundations and corporate entities. Clients have focused on an array of areas including child care, homeless, hunger and K-12 education. Additionally, he is a Freedom of Information Act expert, who has helped numerous clients with securing proprietary information from the federal government. Currently, Frank Klimko writes the Children & Youth Funding Report and Private Grants Alert, which are Washington DC-based publications. CYF is a daily publication covering Congress, the Education Dept. and the various federal regulatory agencies. PGA, another daily publication, covers the world of private philanthropy.
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